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Part I. An Overview of Lipoproteins

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What are Lipoproteins?

Lipoproteins are roughly spherical particles with a lipid core composed mainly of triglycerides, cholesterol ester, and a surface layer containing phospholipid, cholesterol, and protein [11].

When lipids (cholesterol, triglycerides) are absorbed by intestinal cells after a meal, they travel in the bloodstream as constituents of lipoproteins due to their poor solubility in the bloodstream; their hydrophilic components are made soluble by attachment to proteins and phospholipids.

Lipoproteins travel throughout the blood, delivering attached lipids to all the parts of the body.

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